Optimal Adrenal Support

$32.99 or $32.99 $29.69 / month

(2 customer reviews)

Formulated for those who are “stressed and tired.” Dr. Joe’s Optimal Adrenal Support includes a blend of key micronutrients and adaptogenic botanicals formulated to strengthen the body’s stress response and support healthy energy levels.

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60 capsules per bottle. Extended periods of stress not only burden the stress response system but can also result in mental and physical fatigue, nervousness, irritability, and poor memory. Rhodiola Rosea root extract is categorized as an adaptogenic botanical due to its ability to increase resistance to a variety of stressors. Within the central nervous system, Rhodiola has been shown to preserve levels of neurotransmitters such as serotonin, dopamine, and norepinephrine. Eleuthero root extract is a strong adaptogenic botanical widely used in China to support general health, memory, and endurance. In addition to improving stress resilience and fighting fatigue, Eleuthero has exhibited immune supporting effects. Schisandra berry extract is a botanical used for centuries in China and Russia to help support mental clarity, stress response, and emotional health. Licorice root extract promotes healthy cortisol levels by inhibiting an enzyme that converts cortisol to its inactive form, cortisone. This is important for individuals who need support for maintaining inflammatory balance. Ashwagandha root extract is a botanical that helps calm the nervous system and supports sleep cycle regulation and healthy thyroid function.


  • Improves stress resilience
  • Supports healthy energy levels
  • Strengthens the body’s stress response
  • Improves mental and physical performance
  • Helps maintain a balanced cortisol-to-DHEA Ratio


2 capsules 1-2 times a day or as recommended by your healthcare professional



Rhodiola rosea Root Extract

Rhodiola rosea has been categorized as an adaptogenic botanical due to its ability to increase resistance to a variety of stressors. Rhodiola has been studied extensively andis widely used in Eastern Europe and Asia to help support the nervous system, mood regulation, mental clarity, work performance and the sleep cycle. Within the central nervous system, Rhodiola has demonstrated an ability to preserve levels of neurotransmitters such as serotonin, dopamine and norepinephrine. In a randomized, double-blind, placebo-controlled study examining the effects of Rhodiola on fatigue and stress, 161 patients aged 19 to 21 years received Rhodiola twice daily resulting in a significant reduction in fatigue. An additional study using Rhodiola extract in students showed significant improvements in mental performance, greater mood stability, and improved sleep patterns.

Eleuthero Root Extract

Eleutherococcus senticosus has been identified as a strong adaptogenic botanical and is widely used in China to support general health, memory and endurance.  In addition to its ability to improve stress resilience and fight fatigue, Eleuthero has exhibited immune supporting effects. In a double–blind study, 45 healthy volunteers received Eleuthero or placebo for 30 days. A cognitive challenge test was given to assess stress response, along with heart rate. Unlike placebo, subjects receiving Eleuthero demonstrated a 40% reduction in heart rate in response to the stressor.  Eleuthero has also been shown to improve performance in runners. In a study on performance athletes, Eleuthero extract (2 or 4 mL) given 30 minutes prior to a race significantly reduced race time (48.7 minutes) compared to the control group (52.6 minutes).

Schizandra Berry Extract

Schizandra is an adaptogenic botanical that has been used for centuries in China and Russia to help support mental clarity, stress response and emotional wellness. In a double-blind, placebo-controlled study, athletes who were given an adaptogenic blend including Schizandra chinensis extract or placebo, had increased concentrations of nitric oxide, a molecule which causes the blood vessels to expand resulting in increased circulation, increased blood flow and nutrients throughout the body and healthy blood pressure.  The researchers concluded that Schizandra enhances physical performance in athletes. Schizandra berry has been shown to support learning and memory and may have a protective effect on brain health.

Licorice Root Extract

The primary components in licorice root that support adrenal health include glycyrrhetic acid and glycyrrhizin. Licorice has also been shown to block 11-ß-hydroxysteroid dehydrogenase, the enzyme responsible for the conversion of cortisol to the inactive cortisone.  When taken in small doses, licorice root extract can be used to maintain cortisol levels, an important factor for individuals that need to support adrenal hormone production and maintain healthy inflammatory pathways.

Adrenal Concentrate

The use of glandular concentrates to supply key nutrients to support the body has been used in medicine for thousands of years. The concept behind glandular therapy is based on the idea that similar organ extracts from animals will support the same organ within humans by stimulating its activity.

Adrenal bovine concentrate allows for rejuvenation of the adrenal stress system in a balanced and efficient manner.

Micronutrient Blend

Adrenal gland function, as well as the synthesis of cortisol, is dependent on an adequate supply of various vitamins. Vitamin C levels are among the highest in the adrenal glands compared with other organs. Vitamin C plays a major role in neurotransmitter production and supports general health of the adrenals.  Under stressful conditions, vitamin C and B complex vitamins are readily used and excreted from the body. Within the B vitamin family, pantothenic acid breaks down into coenzyme A, which is essential for the production of energy from ingested carbohydrates, fats and proteins. In a study evaluating the effects of pantothenic acid and glutathione production, pantothenic acid was found to increase CoA levels in the body, leading to increased energy production.  Niacin also plays a vital role in many metabolic functions in the body, including supplying energy to cells and assisting in the production of adrenal hormones.


Signs and Symptoms of Deficiencies

The symptoms of adrenal fatigue may include:

  • Tiredness
  • Trouble getting to sleep and waking up
  • Craving salt and sugar
  • unexplained weight loss
  • Reliance on stimulants such as caffeine
  • Nonspecific digestive problems

2 reviews for Optimal Adrenal Support

  1. Ann Clark

    Avid coffee drinker and this really helps to stop me from burning out

  2. Katie Page (verified owner)

    I found this product after listening to several anecdotal stories on the Dr, Joe radio show. I thought it might be helpful for my daughter who is a night nurse and is over stressed, under slept, and does too many things as a constant. She had kept up this pace for far too long and I thought if the adrenal fatigue was a theory this might help. Well it did. Now flash forward to me. I’m a chronic migraine sufferer and I’ve tried almost everything to get under control. I had found some things that helped, but was still in chronic migraine. Its an awful way to live. So I got to reading up on the function of adrenals and they, among other things, control cortisol which in turn controls your hormones. My migraines are largely a part of whacky hormone balances and even with estrogen I couldn’t get it under control, so I thought – why not? I have now been on the adrenal fatigue formula for two wonderous migraine free weeks! I’m not sure its the ‘cure’, but its another tool that helps me cope and that alone makes it worth it to me. I’m a kinda shocked believer.

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